Octet BLI-based Systems vs. SPR

Octet BLI-based Systems vs. SPR Bio-Layer Interferometry (BLI) and Surface plasmon resonance (SPR) are two well-established techniques for detection and monitoring biomolecular interactions in real time. Used orthogonally, they can be powerful and complementary tools in basic research, drug discovery and development, and downstream bioprocessing. While both SPR and BLI utilize light to make real-time […]


Methods for Detection and Analysis of Protein Protein Interactions

Methods for Detection and Analysis of Protein Protein Interactions Protein-protein interactions (PPIs) are the basis of many important cellular processes such as signal transduction, molecular transport and various metabolism pathways, while aberrant PPIs are the basis of multiple aggregation-related diseases, such as Alzheimer’s disease, and may lead to cancer. Therefore, PPIs have been studied extensively in […]